SIGNATURE WORK
CONFERENCE & EXHIBITION 2022

Previous studies, mostly among adults younger than 80 years old, found that higher heart rate (HR) was associated with higher all-cause mortality. We aimed to assess the effect of HR on mortality among Chinese adults aged between 80 and 99 by sex. A total of 22,525 participants (10,405 men, 12,120 women) recruited from 1998-2014 in the first seven waves of the Chinese Longitudinal Healthy Longevity Survey was followed up until 2018. HR measured by blood pressure monitor was classified into four groups: = 90 (n=1,563) beat per minute. The main analyses adjusted for age, marital status, residence, co-residence, diet, physical activity, smoking and drinking. In multivariable-adjusted Cox proportional hazard regression models, the hazard ratio (95% confidence interval) for mortality was 1.04 (1.00-1.08), 1.08 (1.03-1.13), and 1.16 (1.09-1.24) for those in the 70-79, 80-89, and >= 90 groups respectively, compared with the lowest HR group. Results were consistent for both men and women and robust after additional adjustment for cognition, disease history, and physical functioning. In conclusion, higher HR was associated with a higher risk of mortality in Chinese adults aged 80 to 99 years old.