| Monkeypox is a rare but potentially fatal disease caused by the monkeypox virus, which belongs to the same family as smallpox. There is currently no specific treatment or vaccine for monkeypox, making it a significant public health concern. In this research project, we aimed to predict the structure and drug binding results of monkeypox proteins using AlphaFold and AutoDock. We obtained the genome data of 200 monkeypox viruses from approximately 500 different species. We used AlphaFold to predict the structure of these proteins. Our study found that AlphaFold was effective in predicting the structure and drug binding results of monkeypox proteins. The predicted structures were consistent with previous experimental findings, indicating that AlphaFold can be used as a reliable tool for predicting protein structures. By predicting the structure and drug binding results of monkeypox proteins using AutoDock, we have identified potential drug targets that could be used to develop new therapies for this disease. |
