“The primary goal of the study is to examine the biological potential of complexes having phenanthroline/fə’nænθrəli:n/ ligands with fluoro units connected to a Ruthenium (Ru) core. Although platinum medications have been demonstrated to have severe side effects, such as omiting, losing hair, and neurotoxicity, ruthenium compounds have been extensively explored as potential replacements to platinum for clinical development. Ruthenium (II)-centered compounds have garnered the most interest among these metal centers due to their low toxicity, moderate side effects, strong selectivity for healthy cells and tissues, and potent anticancer activity. We want to synthesize a novel metal complex whose structure is comparable to TLD-1433 and its derivatives, but with a different functional group involving the presence of a fluorine atom. The potential biological target of metal complexes is evaluated by how they interact with DNA. “ |